The treatment of this condition is currently centered on dopaminergic tone in the corpus striatum of the brain since a shortfall in dopamine stimulation of these neurons is thought to be responsible for the motor features of PD. The reason for this shortfall is the loss of dopaminergic neurons in the substantia nigra (specifically, the […]
Recent Advancements in Treatment for Parkinson’s Disease Read More »
The protective effects of HDL are linked to the enzyme paraoxonase 1 (PON1), which catalyzes anti-oxidative reactions through its arylesterase (AE) activity. Furthermore, 95% of PON1 found in the serum is bound to HDL through the formation of an HDL-PON1 complex. This complex is partially regulated by the phospholipase endothelial lipase (EL). This enzyme hydrolyzes
Monitoring the relationship between Endothelial Lipase and HDL by NMR Read More »
Diversity in clinical trials is an important issue as the effectiveness of a drug in one population doesn’t always indicate that it will be as effective in other populations or that it will even be safe in other groups. If a drug is approved to be effective and is licensed for a disease it is
Why is Diversity Critical for Clinical Trials? Read More »
